Upneeq is the only FDA-approved prescription eyedrop for acquired ptosis (low-lying lids) that lifts your upper eyelids to open your eyes. The drop starts working in 15-30 minutes and lasts up to 8 hours. Unneeq is a great option for those who are a good candidate to help relieve droopy eyelids and tired-looking eyes, or to brighten up the eyes for an important event! Upneeq is not recommended for patients who are pregnant or breastfeeding, or those with untreated high blood pressure or glaucoma.